 |
| 3 types of chemical pathways |
Hey guys, here's the link to my podcast on HGH growth hormone if you want to listen. Below is the transcript, thanks for the support!
"Hey guys, welcome to another episode of 'Helix Affinity' podcast, and I’m your host Andy. And today, to celebrate the Sochi Winter Olympics, and continue our topic of the endocrine system, we will be talking about a hormone that can improve the performance of athletes, which is HGH, the Human Growth Hormone.
This is a peptide water-soluble hormone that is responsible for cell regeneration, reproduction and growth of bones, muscles and other tissues. It is produced on the anterior pituitary gland in endocrine system.
To understand how this hormone works, it is important to understand what “chemical pathway” means.
The chemical pathway is a bio-chemical reaction that occurs in a cell. Photosynthesis, cell respiration, these reactions are both chemical pathways. So the pathway begins with a receptor that detects the stimulus and send the information to a control center, and the control center would send out a signal that directs at the target cell.
In the endocrine and neuroendocrine, two major types of chemical pathways, that signal would be the hormone. So, how exactly does the HGH work?
The Growth Hormone has two types of effects. The first effect would be direct effect that the hormone binds the receptor on the target cells. An example would be adipocytes, the fat cells. With growth hormone receptors on the cells, HGH would stimulate the receptors to suppress the cell’s ability to accumulate lipids by breaking down triglycerides.
Another effect of Growth Hormone would be indirect effect, that the hormone travels to the liver and induces the production of IGF-1, the insulin-like growth factor that creates a negative loop to stimulate amino acid uptake and protein synthesis in muscles and other tissues.
The IGF-1 also takes part in the regulatory system of HGH, that high amount of IGF-1 stimulates the secretion of somatostatin, the inhibitor of HGH. Another regulator would be GHRH, the information of hormone that stimulates the production of HGH.
So at this point you may wonder, what’s the difference between growth hormone and steroids? First of all, HGH is not for medical use, since it’s already in your body, while steroid is. Also, HGH is easier to absorb than steroids. It is not addictive, and has no side effects.
With these characters, HGH is often revered as “fountain of youth”, but it is still restricted in the Olympics. Growth hormone injections have been used by athletes since 1982, and they are still banned by IOC and NCAA.
Since the traditional urine test could not detect HGH, the law wasn’t enacted until early 2000s, when a new blood test found the difference between natural and artificial HGH. Finally, the blood test was first used in 2004 Olympics Games in Athens, Greece.
Thank you for listening to the Olympic special episode of 'Helix Affinity', and we’ll see you next week, stay healthy. " |
| Feedback Loop of HGH hormone |
Works Cited:
Bowen, R. "Growth Hormone." Growth Hormone. N.p., n.d. Web. 22 Feb. 2014. Retrieved from URL: http://arbl.cvmbs.colostate.edu/hbooks/pathphys/endocrine/hypopit/gh.html
"Steroids Forum: HGH & Peptides/rHGH/A Basic Guide to Human Growth Hormone."Steroids Forum: HGH & Peptides/rHGH/A Basic Guide to Human Growth Hormone. N.p., 31 Aug. 2012. Web. 24 Feb. 2014. Retrieved from URL: http://www.eroids.com/forum/hgh-peptides/rhgh/a-basic-guide-to-human-growth-hormone
"HGH (Human Growth Hormone): Uses and Side Effects." WebMD. WebMD, n.d. Web. 23 Feb. 2014. Retrieved from URL: http://www.webmd.com/fitness-exercise/human-growth-hormone-hgh
Background Music: Harder Better Faster Stronger by Daft Punk
- Andy Liu '15
No comments:
Post a Comment